Sunday afternoon, July, 8

1. Multiple endpoints in clinical trials (increasing popularity of multiple and composite endpoints to describe diseases with a "multidimensional" etiology)
2. Global tests
   • Basic global tests (stepwise tests based on univariate p-values, Tukey-Ciminera-Heyse test)
   • Global tests that account for correlation structure of multiple endpoints (tests based on the assumption of multivariate normality and resampling-based tests)
3. Inferences for individual endpoints
   • Analysis of individual endpoints (identification of treatment effect on individual components of composite endpoints)
   • Multiple tests for individual endpoints (multivariate-normal and resampling-based tests)
4. Gatekeeping and related testing procedures in clinical trials
   • Analysis of clinical trials with multiple objectives (multiple primary and secondary endpoints, multiple dose-control comparisons, multidimensional objectives)
5. Gatekeeping strategies in clinical trials
   
   • Serial and parallel gatekeeping procedures (derivation of serial and parallel gatekeeping procedures based on the closed testing principle, Bonferroni-based procedures, resampling-based procedures, stepwise procedures)
   • Gatekeeping procedures in clinical trials with multiple primary and secondary endpoints and dose-finding studies
6. Tree gatekeeping procedures
   
   • Flexible multiple tests for clinical trials with hierarchical objectives (derivation of tree gatekeeping procedures based on the closed testing principle)
   • Resampling-based tree gatekeeping procedures (application of Westfall-Young methodology)
   • Tree gatekeeping procedures clinical trials with multiple endpoints