Fong Wang-Clow (Genentech, Inc., USA)
Alternative Approaches of Multiple Comparisons in Clinical Trials
There are a lot of types of multiple comparison in clinical trial. This presentation will provide four types of multiple comparisons and their applications in clinical trials. This presentation also shows how the needs of medical and clinical drive the use of the alternative approaches as opposing to the classical approaches.
- Bauer, P. (1991) "Multiple Testing in clinical Trials" Statistics in Medicine Vol. 10, 871-890
- Dunnett, W.C. and Gent,M. (1996) "An alternative to the use of two-sided tests in clincial trials" Statistics in Medicine Vol.15, 1729-1738
- Fleming, T.R. (1990) "Evaluation of active control trials in AIDS" Journal of Acquired Immune Deficiency Syndromes 3(Suppl.2):S82-87
- Koch,G.G. Sansky,S.A. (1994) "Statistical considerations for multiple confirmatory protocols" DIA Workshop